Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177383 | 0.81 | KIF11 (0.35) | NOTUMKIF11MEN1KMT2ATAS2R14 | |
| SCHEMBL28387002 | 0.78 | HSP90AA1 (0.35) | KIF11HTR2AHTR2C | |
| SCHEMBL28645960 | 0.77 | MEN1 (0.36) | KIF11MEN1KMT2AMAPTLMNA | |
| SCHEMBL17796987 | 0.75 | SLC1A3 (0.38) | KIF11MEN1KMT2AHTTNPC1 | |
| SCHEMBL29236517 | 0.73 | IDO1 (0.33) | KIF11MEN1KMT2AMAPTDGAT1 | |
| SCHEMBL28892767 | 0.72 | HTR2A (0.44) | LMNAHTTRAB9AHTR2AHTR2C | |
| SCHEMBL29177250 | 0.71 | EPHX2 (0.45) | KIF11MEN1KMT2A | |
| SCHEMBL31145404 | 0.71 | DGAT1 (0.49) | NOTUMKIF11MEN1KMT2AMAPT | |
| SCHEMBL22093024 | 0.71 | DGAT1 (0.49) | NOTUMKIF11MEN1KMT2AMAPT | |
| SCHEMBL9227013 | 0.70 | NOTUM (0.36) | NOTUMKIF11MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107250110-B | Novel compounds as inhibitors of transfection Rearrangement (RET) | 葛兰素史克知识产权发展有限公司 | 2020-04-24 | — | — | CN | disclosed |