Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.61 |
| ▸ | IDE | P14735 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28867147 | 0.86 | G6PD (0.47) | G6PDIDEALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL898422 | 0.79 | G6PD (0.64) | G6PDIDEALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL634380 | 0.78 | GAA (0.70) | G6PDIDEALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL1368132 | 0.75 | G6PD (0.55) | G6PDIDEALDH1A1GAAMAPT | |
| SCHEMBL9538632 | 0.74 | G6PD (0.58) | G6PDIDEALDH1A1CA12CA1 | |
| SCHEMBL1371008 | 0.73 | G6PD (0.53) | G6PDIDEALDH1A1CA12CA1 | |
| SCHEMBL11820341 | 0.73 | G6PD (0.53) | G6PDIDEALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL1370002 | 0.73 | LMNA (0.55) | G6PDIDEALDH1A1MAPTCA12 | |
| SCHEMBL1371001 | 0.73 | G6PD (0.53) | G6PDIDEGAAMAPTCA12 | |
| SCHEMBL1006804 | 0.73 | G6PD (0.53) | G6PDIDEALDH1A1HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111039898-B | Preparation method of metopimazine intermediate | 暨明医药科技（苏州）有限公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-111039898-A | Preparation method of metopimazine intermediate | 暨明医药科技（苏州）有限公司 | 2020-04-21 | — | — | CN | disclosed |