Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.58 |
| ▸ | IDE | P14735 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 14/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536854 | 0.80 | PTGS2 (0.52) | PTGS2PTGS1PTGDR2 | |
| SCHEMBL9537442 | 0.80 | PTGS2 (0.58) | G6PDIDEPTGS2PTGS1PTGDR2 | |
| SCHEMBL28867147 | 0.75 | G6PD (0.47) | G6PDIDEPTGS2PTGS1ALDH1A1 | |
| SCHEMBL9534604 | 0.75 | ALDH1A1 (0.44) | ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL28385019 | 0.74 | G6PD (0.61) | G6PDIDEPTGS2PTGS1ALDH1A1 | |
| SCHEMBL9535502 | 0.74 | MAPT (0.46) | PTGS2ALDH1A1 | |
| SCHEMBL9534376 | 0.72 | MAPK14 (0.46) | PTGS2ALDH1A1 | |
| SCHEMBL221279 | 0.72 | CA1 (0.68) | G6PDIDEPTGS2ALDH1A1CA12 | |
| SCHEMBL576377 | 0.72 | ALDH1A1 (0.46) | PTGS2PTGS1ALDH1A1CA6CA5A | |
| SCHEMBL30452220 | 0.72 | ALDH1A1 (0.46) | PTGS2PTGS1ALDH1A1CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |