Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28385019 | 0.86 | G6PD (0.61) | G6PDIDESLC6A4SLC6A2PTGS2 | |
| SCHEMBL28503304 | 0.79 | MAPT (0.56) | SLC6A4SLC6A2ALDH1A1HPGDSLC6A3 | |
| SCHEMBL2969774 | 0.76 | SLC6A4 (0.62) | SLC6A4SLC6A2ALDH1A1HSD17B10SLC6A3 | |
| SCHEMBL9538632 | 0.75 | G6PD (0.58) | G6PDIDESLC6A4SLC6A2PTGS2 | |
| SCHEMBL1371008 | 0.73 | G6PD (0.53) | G6PDIDEPTGS2ALDH1A1KIF11 | |
| SCHEMBL30567146 | 0.73 | MEN1 (0.52) | SLC6A4SLC6A2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL1341376 | 0.73 | MEN1 (0.52) | SLC6A4SLC6A2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11090117 | 0.70 | MAPT (0.43) | SLC6A4SLC6A2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL221279 | 0.70 | CA1 (0.68) | G6PDIDEPTGS2ALDH1A1KIF11 | |
| SCHEMBL24220370 | 0.70 | KDM4E (0.56) | ALDH1A1HPGDTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053716-A | A kind of new process preparing metopimazine | 暨明医药科技（苏州）有限公司 | 2018-12-21 | — | — | CN | claimed |