4-Cyanophenol

4-Cyanophenol

SCHEMBL28386261

N#Cc1ccc(O)cc1.O=S(=O)(O)C(F)(F)F

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.61
CA9 Q16790 3/20 0.61
CA12 O43570 2/20 0.61
CA3 P07451 1/20 0.61
CA6 P23280 1/20 0.61
CA14 Q9ULX7 1/20 0.61
MMP3 P08254 1/20 0.55
P4HB P07237 1/20 0.42
CYP19A1 P11511 1/20 0.42
KIF11 P52732 1/20 0.41
PTPN5 P54829 1/20 0.41
TRPV4 Q9HBA0 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
SLC22A12 Q96S37 2/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CA1 P00915 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL576036 0.83 LMNA (0.52) CA2CA9CA12CA3CA14
Benzonitrile SCHEMBL27664681 0.82 TSHR (0.56) KIF11PTPN5TRPV4HDAC1HDAC7
Trifluoromethanesulfonic Acid SCHEMBL2826879 0.80 PTPN5 (0.53) CA2CA9CA12MMP3KIF11
Isonicotinonitrile SCHEMBL669363 0.79 SLC22A12 (0.48) CA2CA9CA12CYP19A1KIF11
4-Cyanophenol SCHEMBL28811803 0.78 CA2 (1.00) CA2CA9CA12CA3CA6
4-Cyanophenol SCHEMBL50814 0.78
4-Cyanophenol SCHEMBL27294505 0.78 CA2 (1.00) CA2CA9CA12CA3CA6
Trifluoromethanesulfonic Acid SCHEMBL1713466 0.77 KIF11 (0.54) CA2CA9CA12MMP3KIF11
4-Cyanophenol SCHEMBL27652227 0.77 CA2 (0.84) CA2CA9CA12CA3CA6
4-Cyanophenol SCHEMBL4820911 0.77 CA2 (0.84) CA2CA9CA12CA3CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110903316-B Phosphonate compound and preparation method and application thereof 中南大学 2021-03-02 CN claimed
CN-110903316-A Phosphonate compound and preparation method and application thereof 中南大学 2020-03-24 CN claimed
CN-110903316-B Phosphonate compound and preparation method and application thereof 中南大学 2021-03-02 CN disclosed
CN-110903316-A Phosphonate compound and preparation method and application thereof 中南大学 2020-03-24 CN disclosed