SCHEMBL28388285

SCHEMBL28388285

O=C1N=C(c2ccc(O)cc2)c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.43
BACE1 P56817 1/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
MAPT P10636 4/20 0.42
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HPGDS O60760 1/20 0.42
PKM P14618 1/20 0.42
MAOB P27338 1/20 0.42
ABL1 P00519 1/20 0.42
ABCB1 P08183 1/20 0.42
BCR P11274 1/20 0.42
MMP3 P08254 1/20 0.41
BCL2L1 Q07817 1/20 0.41
KDM4E B2RXH2 1/20 0.40
LMNA P02545 2/20 0.39
GAA P10253 2/20 0.39
ESR2 Q92731 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11297168 0.84 MAPT (0.51) PTPN1BACE1MEN1KMT2AMAPT
SCHEMBL5579205 0.81 RAB9A (0.42) MEN1KMT2AMAPTRAB9ANPC1
SCHEMBL22770028 0.78 MAPT (0.44) MAPTRAB9ANPC1SMN1; SMN2MAOB
SCHEMBL22769968 0.77 BACE1 (0.49) BACE1KMT2AMAPTMAOBKDM4E
SCHEMBL20681466 0.77 HDAC4 (0.50) PTPN1BACE1MEN1KMT2AMAPT
SCHEMBL21253173 0.72 MAPT (0.38) MAPTLMNAGAARPS6KA3
SCHEMBL21253038 0.72 PDK2 (0.40) RAB9ANPC1HPGDSPKM
SCHEMBL13945302 0.70 MIF (0.44) PTPN1BACE1MEN1KMT2AMAPT
Phthalimide SCHEMBL1388700 0.70 APAF1 (0.44) BACE1MEN1KMT2AMAPTRAB9A
SCHEMBL3101579 0.69 PDE3B (0.46) PTPN1MEN1KMT2AMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861407-B Polymer, composition, and molded article JSR株式会社 2024-02-20 CN disclosed
CN-115449204-A Thermoplastic compositions, articles comprising the same, and methods of forming 高新特殊工程塑料全球技术有限公司 2022-12-09 CN disclosed
CN-115190895-A High heat polycarbonate copolymer formulations 高新特殊工程塑料全球技术有限公司 2022-10-14 CN disclosed
CN-111417668-B Benzopyrrolo copolycarbonate optical articles, articles formed therefrom, and methods of making the same 高新特殊工程塑料全球技术有限公司 2022-06-28 CN disclosed
CN-109071804-B Polymer, composition, molded body, cured product, and laminate JSR株式会社 2022-01-11 CN disclosed
CN-113861407-A Polymer, composition, and molded article JSR株式会社 2021-12-31 CN disclosed
CN-113195636-A Polycarbonate compositions and related articles and additive manufacturing methods 高新特殊工程塑料全球技术有限公司 2021-07-30 CN disclosed
CN-112574572-A Low temperature foamable polycarbonate compositions and articles thereof 沙特基础工业全球技术有限公司 2021-03-30 CN disclosed
CN-105324425-B Polycarbonate composition for producing optical quality products with high quality and good processability 沙特基础全球技术有限公司 2021-02-09 CN disclosed
CN-111684864-A Transparent electromagnetic shielding panel and assembly comprising same 沙特基础工业全球技术有限公司 2020-09-18 CN disclosed
CN-111417668-A Benzo [ c ] pyrrolidone copolycarbonate optical articles, articles formed therefrom and methods of making same 沙特基础工业全球技术有限公司 2020-07-14 CN disclosed
CN-107531901-B Polyetherimide miscible polymer blends for capacitor films 沙特基础全球技术有限公司 2020-04-17 CN disclosed