Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22770028 | 0.85 | MAPT (0.44) | MAPTLMNAGAAIDO1CDK2 | |
| SCHEMBL28388285 | 0.84 | PTPN1 (0.43) | MAPTLMNAGAAALDH1A1NPC1 | |
| SCHEMBL5579205 | 0.84 | RAB9A (0.42) | MAPTLMNAGAAALDH1A1TSHR | |
| SCHEMBL1826641 | 0.84 | MAOB (0.42) | MAPTLMNAGAAALDH1A1TSHR | |
| SCHEMBL22769968 | 0.79 | BACE1 (0.49) | MAPTCCKBRALDH1A1TSHRBACE1 | |
| SCHEMBL20681466 | 0.79 | HDAC4 (0.50) | MAPTIDO1CCNE2CCNE1CDK2 | |
| SCHEMBL3101579 | 0.79 | PDE3B (0.46) | MAPTLMNAGAAHTTTSHR | |
| SCHEMBL16058512 | 0.75 | AKT2 (0.48) | MAPTLMNAGAA | |
| SCHEMBL21253038 | 0.74 | PDK2 (0.40) | NPC1RAB9APKM | |
| SCHEMBL21253173 | 0.74 | MAPT (0.38) | MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56018920-A | — | — | None | — | — | JP | disclosed |
| CN-116546990-B | CD73 inhibitor and pharmaceutical application thereof | RISEN (SUZHOU) PHARMA TECH Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | SIRONAX LTD (KY) | 2026-03-19 | — | — | US | disclosed |
| EP-4590674-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2025-07-30 | — | — | EP | disclosed |
| CN-114539340-B | CD73 inhibitor and pharmaceutical application thereof | 润佳（苏州）医药科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-11998901-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | INSTITUTE FOR BASIC SCIENCE (KR) | 2024-06-04 | — | — | US | disclosed |
| WO-2024061340-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-03-28 | — | — | WO | disclosed |
| US-20240024346-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | RISEN SUZHOU PHARMA TECH CO LTD (CN) | 2024-01-25 | — | — | US | disclosed |
| US-20230295213-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | RISEN SUZHOU PHARMA TECH CO LTD (CN) | 2023-09-21 | — | — | US | disclosed |
| CN-116546990-A | CD73 inhibitor and pharmaceutical application thereof | 润佳（苏州）医药科技有限公司 | 2023-08-04 | — | — | CN | disclosed |
| US-20210060915-A1 | TRANSPARENT, FLEXIBLE, IMPACT RESISTANT, MULTILAYER FILM COMPRISING POLYCARBONATE COPOLYMERS | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2021-03-04 | — | — | US | disclosed |
| EP-3750885-A1 | COMPOUND HAVING BET INHIBITORY ACTIVITY AND PREPARATION METHOD AND USE THEREFOR | Shanghai Haihe Pharmaceutical Co., Ltd. (CN) | 2020-12-16 | — | — | EP | disclosed |
| US-20200330969-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-10-22 | — | — | US | disclosed |
| CN-111683932-A | Compound with BET inhibition activity, preparation method and application thereof | 上海海和药物研究开发有限公司 | 2020-09-18 | — | — | CN | disclosed |
| CN-111566116-A | Novel metal complex, method for producing same, and method for producing gamma-lactam compound using same | 基础科学研究院 | 2020-08-21 | — | — | CN | disclosed |
| WO-2019135600-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | 기초과학연구원 | 2019-07-11 | — | — | WO | disclosed |
| US-20190127574-A1 | POLY(ESTER-CARBONATE) COPOLYMERS, ARTICLES FORMED THEREFROM, AND METHODS OF MANUFACTURE | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-05-02 | — | — | US | disclosed |
| EP-2810309-A1 | LIGHT EMITTING DIODE DEVICE AND METHOD FOR PRODUCTION THEREOF CONTAINING CONVERSION MATERIAL CHEMISTRY | SABIC Innovative Plastics IP B.V. (NL) | 2014-12-10 | — | — | EP | disclosed |
| WO-2013116697-A1 | LIGHT EMITTING DIODE DEVICE AND METHOD FOR PRODUCTION THEREOF CONTAINING CONVERSION MATERIAL CHEMISTRY | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-08-08 | — | — | WO | disclosed |
| JP-S5618920-A | ANTI-INFALMMATORY CONTAINING 3-PHENYLISOINDOLIN-1-ONE DERIVATIVE AS THE EFFECTIVE COMPONENT | MITSUBISHI CHEM IND LTD | 1981-02-23 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | NAMPT, NNMT, SARM1 | MAPT 523/4885LMNA 287/4885GAA 3156/4885 |
| US-20230295213-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | ENTPD5, NT5E, ENTPD1 | MAPT 3578/4885LMNA 2144/4885GAA 223/4885 |
| US-20240024346-A1 | CD73 INHIBITORS AND PHARMACEUTICAL USES THEREOF | ENTPD5, NT5E, ENTPD1 | MAPT 3578/4885LMNA 2144/4885GAA 223/4885 |
| US-11998901-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | COASY, NOTUM, MRPL21 | MAPT 2937/4885LMNA 4102/4885GAA 105/4885 |
| US-20200330969-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | COASY, NOTUM, MRPL21 | MAPT 2868/4885LMNA 4193/4885GAA 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.