Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11297168 | 0.84 | MAPT (0.51) | RAB9ANPC1PKMTSHRAGTR1 | |
| SCHEMBL28388285 | 0.81 | PTPN1 (0.43) | RAB9ANPC1PKMHPGDSMEN1 | |
| SCHEMBL20681466 | 0.80 | HDAC4 (0.50) | RAB9ANPC1PKMTP53TSHR | |
| SCHEMBL12912969 | 0.80 | NPC1 (0.46) | RAB9ANPC1PKMTP53MAPK1 | |
| SCHEMBL21253038 | 0.79 | PDK2 (0.40) | RAB9ANPC1PKMHPGDSELANE | |
| SCHEMBL22770028 | 0.78 | MAPT (0.44) | RAB9ANPC1TP53TSHRPOLB | |
| SCHEMBL22769968 | 0.77 | BACE1 (0.49) | TP53TSHRKMT2APOLBALDH1A1 | |
| SCHEMBL12912867 | 0.76 | IDO1 (0.50) | RAB9ANPC1PKMTP53MAPK1 | |
| SCHEMBL28428006 | 0.74 | ALDH1A1 (0.54) | RAB9ANPC1PKMTP53MAPK1 | |
| SCHEMBL1443789 | 0.73 | L3MBTL1 (0.47) | RAB9ANPC1TP53MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | disclosed |