Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | STK10 | O94804 | 1/20 | 0.37 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28063135 | 0.81 | MCL1 (0.46) | MCL1CA1CA2NCOA3KDM4E | |
| SCHEMBL28384020 | 0.79 | IMPDH2 (0.51) | MCL1CA1CA2KDM4ESLC22A12 | |
| SCHEMBL13170778 | 0.78 | CA1 (0.55) | MCL1CA1CA2KDM4EALOX15 | |
| SCHEMBL19435572 | 0.76 | SLC22A12 (0.51) | MCL1CA1CA2KDM4EANPEP | |
| SCHEMBL29110490 | 0.76 | MCL1 (0.49) | MCL1CA1CA2KDM4EALOX15 | |
| SCHEMBL29039496 | 0.75 | CA1 (0.50) | MCL1CA1CA2KDM4EALOX15 | |
| SCHEMBL20561064 | 0.74 | MCL1 (0.58) | MCL1CA1CA2KDM4EALOX15 | |
| SCHEMBL2353695 | 0.74 | CA1 (0.53) | MCL1CA1CA2KDM4EALOX15 | |
| SCHEMBL31236642 | 0.74 | MCL1 (0.58) | MCL1CA1CA2KDM4EALOX15 | |
| SCHEMBL29489130 | 0.73 | MCL1 (0.47) | MCL1CA1CA2NCOA3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108478-B | URAT1 inhibitors | 日本化学药品株式会社 | 2020-04-24 | — | — | CN | disclosed |