Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29741124 | 0.84 | ALDH1A1 (0.46) | SMN1; SMN2LMNAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL21606969 | 0.78 | GABRA1 (0.36) | SMN1; SMN2MAPTCYP1A2GABRG2GABRB3 | |
| SCHEMBL25983777 | 0.78 | GPR35 (0.39) | SMN1; SMN2ALDH1A1NPC1RAB9AGABRG2 | |
| SCHEMBL7871704 | 0.77 | HSP90AA1 (0.41) | SMN1; SMN2LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29741278 | 0.76 | CYP1A2 (0.41) | SMN1; SMN2LMNAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL3640842 | 0.76 | CYP1A2 (0.41) | SMN1; SMN2LMNAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1671268 | 0.76 | L3MBTL1 (0.44) | SMN1; SMN2LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2685253 | 0.76 | HSP90AA1 (0.43) | SMN1; SMN2LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29983622 | 0.76 | HSP90AA1 (0.43) | SMN1; SMN2LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL827852 | 0.76 | PDE2A (0.38) | SMN1; SMN2LMNATAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072554-B | Synthesis method of 4-bromo-2-chloro-6-methoxypyridine | 郑州华赞医药科技有限公司 | 2023-06-16 | — | — | CN | claimed |
| CN-111072554-A | Synthesis method of 4-bromo-2-chloro-6-methoxypyridine | 郑州华赞医药科技有限公司 | 2020-04-28 | — | — | CN | claimed |
| CN-111072554-B | Synthesis method of 4-bromo-2-chloro-6-methoxypyridine | 郑州华赞医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-111072554-B | Synthesis method of 4-bromo-2-chloro-6-methoxypyridine | 郑州华赞医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-111072554-B | Synthesis method of 4-bromo-2-chloro-6-methoxypyridine | 郑州华赞医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-111072554-A | Synthesis method of 4-bromo-2-chloro-6-methoxypyridine | 郑州华赞医药科技有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-111072554-A | Synthesis method of 4-bromo-2-chloro-6-methoxypyridine | 郑州华赞医药科技有限公司 | 2020-04-28 | — | — | CN | disclosed |
| CN-111072554-A | Synthesis method of 4-bromo-2-chloro-6-methoxypyridine | 郑州华赞医药科技有限公司 | 2020-04-28 | — | — | CN | disclosed |