Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28394721 | 0.91 | ADAMTS5 (0.43) | ADAMTS5MMP2MAPTALDH1A1LMNA | |
| SCHEMBL28401171 | 0.89 | LMNA (0.45) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28391828 | 0.87 | KMT2A (0.50) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28400024 | 0.84 | LMNA (0.43) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28397526 | 0.83 | ALDH1A1 (0.49) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28396618 | 0.82 | SMN1; SMN2 (0.51) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28391953 | 0.82 | L3MBTL1 (0.53) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28405211 | 0.81 | ADAMTS5 (0.43) | ADAMTS5MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL28392352 | 0.80 | TP53 (0.51) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28394817 | 0.80 | TP53 (0.40) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822126-B | Thienopyran formyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-05-15 | — | — | CN | claimed |
| CN-108822126-B | Thienopyran formyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-05-15 | — | — | CN | disclosed |