Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28397524 | 0.89 | ALDH1A1 (0.46) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28393540 | 0.89 | KMT2A (0.55) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28393014 | 0.88 | ALDH1A1 (0.45) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28391829 | 0.87 | ALDH1A1 (0.51) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28397525 | 0.86 | LMNA (0.53) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28396620 | 0.84 | POLB (0.48) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28392977 | 0.83 | NOTUM (0.42) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28888486 | 0.83 | L3MBTL1 (0.45) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28394808 | 0.83 | GAA (0.51) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL28394262 | 0.83 | L3MBTL1 (0.43) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822126-B | Thienopyran formyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-05-15 | — | — | CN | claimed |
| CN-108822126-B | Thienopyran formyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-05-15 | — | — | CN | disclosed |