Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 10/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28397428 | 0.94 | KAT6A (0.47) | ALOX5MAOBKAT6AALDH1A1LMNA | |
| SCHEMBL28400817 | 0.88 | MAOB (0.52) | MAOBMAOA | |
| SCHEMBL31166954 | 0.86 | ALOX5 (0.58) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL28397085 | 0.84 | MAPK1 (0.42) | MAOASMN1; SMN2 | |
| SCHEMBL28402703 | 0.81 | MAOB (0.65) | ALOX5MAOBMAOA | |
| SCHEMBL28396179 | 0.80 | LMNA (0.60) | ALOX5MAOBLMNACYP1A2PTGS1 | |
| SCHEMBL27392692 | 0.79 | KAT6A (0.46) | MAOBKAT6AMAOA | |
| SCHEMBL15365 | 0.79 | MAOB (0.58) | ALOX5MAOBALDH1A1LMNACYP1A2 | |
| SCHEMBL28396007 | 0.79 | MAOB (0.62) | ALOX5MAOBMAOA | |
| SCHEMBL28406655 | 0.78 | MEN1 (0.47) | ALOX5MAOBALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107344940-B | BTK inhibitors and uses thereof | 广东东阳光药业有限公司 | 2020-04-21 | — | — | CN | disclosed |