SCHEMBL28396285

SCHEMBL28396285

ClC(Cl)(Cl)c1ncnc(C=Cc2ccco2)n1.c1cnnnc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.43
MAPT P10636 10/20 0.37
KMT2A Q03164 9/20 0.37
MEN1 O00255 8/20 0.37
KDM4E B2RXH2 8/20 0.37
POLB P06746 8/20 0.37
NPC1 O15118 7/20 0.37
TDP1 Q9NUW8 7/20 0.37
RAB9A P51151 6/20 0.37
L3MBTL1 Q9Y468 6/20 0.37
RECQL P46063 5/20 0.37
BLM P54132 4/20 0.37
MCL1 Q07820 2/20 0.37
ALDH1A1 P00352 5/20 0.33
LMNA P02545 5/20 0.32
SMN1; SMN2 Q16637 4/20 0.32
HPGD P15428 3/20 0.32
HTT P42858 3/20 0.32
NPSR1 Q6W5P4 2/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21603035 0.92 GRM4 (0.46) GRM4MAPTKMT2AMEN1KDM4E
SCHEMBL28415178 0.88 GRM4 (0.43) GRM4MAPTKMT2AMEN1KDM4E
SCHEMBL499048 0.78 GRM4 (0.46) GRM4MAPTKMT2AMEN1KDM4E
SCHEMBL499049 0.78 GRM4 (0.46) GRM4MAPTKMT2AMEN1KDM4E
SCHEMBL25801378 0.72 GRM4 (0.41) GRM4MAPTKMT2AMEN1KDM4E
SCHEMBL30724505 0.70 F2 (0.44) GRM4MAPTKMT2AMEN1KDM4E
SCHEMBL5188282 0.69 BRAF (0.41) MAPTKMT2AMEN1KDM4EPOLB
SCHEMBL13742201 0.69 BRAF (0.41) MAPTKMT2AMEN1KDM4EPOLB
SCHEMBL940015 0.69 KDM4E (0.44) GRM4KMT2AMEN1KDM4ENPC1
SCHEMBL940017 0.69 KDM4E (0.44) GRM4KMT2AMEN1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114879296-A Polarizing element and method for manufacturing the same 住友化学株式会社 2022-08-09 CN disclosed
CN-112204438-B Polarizing film, method for producing same, polarizing plate, and display device 住友化学株式会社 2022-08-09 CN disclosed
CN-114839710-A Optical laminate 住友化学株式会社 2022-08-02 CN disclosed
CN-114764158-A Light absorption anisotropic plate 住友化学株式会社 2022-07-19 CN disclosed
CN-114144709-A Polarizing film and method for producing same 住友化学株式会社 2022-03-04 CN disclosed
CN-112789527-A Polarizing film and method for producing same 住友化学株式会社 2021-05-11 CN disclosed
CN-112740084-A Polarizing film and method for producing same 住友化学株式会社 2021-04-30 CN disclosed
CN-112703436-A Polarizing film, polarizing plate comprising same and display device 住友化学株式会社 2021-04-23 CN disclosed
CN-112204438-A Polarizing film, method for producing same, polarizing plate, and display device 住友化学株式会社 2021-01-08 CN disclosed
CN-111971597-A Polymerizable liquid crystal composition 住友化学株式会社 2020-11-20 CN disclosed
CN-111868626-A Photosensitive composition 富士胶片株式会社 2020-10-30 CN disclosed
CN-111771164-A Photosensitive composition 富士胶片株式会社 2020-10-13 CN disclosed
CN-111699422-A Photosensitive composition 富士胶片株式会社 2020-09-22 CN disclosed
CN-111656280-A Photosensitive composition 富士胶片株式会社 2020-09-11 CN disclosed
CN-111656278-A Photosensitive composition 富士胶片株式会社 2020-09-11 CN disclosed
CN-111149021-A Method for manufacturing optical filter 富士胶片株式会社 2020-05-12 CN disclosed
CN-111133381-A Colored photosensitive composition and method for producing optical filter 富士胶片株式会社 2020-05-08 CN disclosed