SCHEMBL499048

SCHEMBL499048

ClC(Cl)(Cl)c1nc(/C=C/c2ccco2)nc(C(Cl)(Cl)Cl)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.46
MEN1 O00255 7/20 0.43
KMT2A Q03164 7/20 0.43
KDM4E B2RXH2 7/20 0.43
MAPT P10636 7/20 0.43
POLB P06746 6/20 0.43
NPC1 O15118 5/20 0.43
RAB9A P51151 5/20 0.43
TDP1 Q9NUW8 3/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
BLM P54132 2/20 0.43
RECQL P46063 1/20 0.43
MCL1 Q07820 1/20 0.43
ALDH1A1 P00352 8/20 0.41
HCAR2 Q8TDS4 1/20 0.39
HPGD P15428 6/20 0.38
HTT P42858 4/20 0.38
LMNA P02545 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
GAA P10253 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL499049 1.00 GRM4 (0.46) GRM4MEN1KMT2AKDM4EMAPT
SCHEMBL30724505 0.90 F2 (0.44) GRM4MEN1KMT2AKDM4EMAPT
SCHEMBL25801378 0.90 GRM4 (0.41) GRM4MEN1KMT2AKDM4EMAPT
SCHEMBL21603035 0.84 GRM4 (0.46) GRM4MEN1KMT2AKDM4EMAPT
SCHEMBL28415178 0.81 GRM4 (0.43) GRM4MEN1KMT2AKDM4EMAPT
SCHEMBL10227013 0.79 MAPT (0.38) GRM4MEN1KMT2AKDM4EMAPT
SCHEMBL25301410 0.79 DOT1L (0.36) GRM4MEN1KMT2AKDM4EMAPT
SCHEMBL28396285 0.78 GRM4 (0.43) GRM4MEN1KMT2AKDM4EMAPT
SCHEMBL26290674 0.75 MEN1 (0.47) GRM4MEN1KMT2AKDM4EMAPT
SCHEMBL641747 0.73 ALDH1A1 (0.62) GRM4MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 993 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240168374-A1 PHOTORESIST COMPOSITION TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2024-05-23 US claimed
US-9244354-B2 Method for producing thick film photoresist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2016-01-26 US claimed
WO-2026100726-A1 DECORATIVE FILM, ELECTRONIC MEMBER, AND TOUCH PAD JSR株式会社 2026-05-15 WO disclosed
US-20260117026-A1 DIELECTRIC MATERIALS BASED ON HETEROAROMATIC-EXTENDED BISMALEIMIDES MERCK PATENT GMBH (DE) 2026-04-30 US disclosed
EP-4346935-B1 COATING FOR MEDICAL DEVICES SMART REACTORS SERVICE LTD (IE) 2026-04-22 EP disclosed
US-20260098128-A1 CURABLE BRANCHED ORGANOPOLYSILOXANE, HIGH ENERGY RAY-CURABLE COMPOSITION CONTAINING SAME, AND USE THEREOF DOW TORAY CO LTD (JP) 2026-04-09 US disclosed
US-20260085194-A1 OPTICAL PRODUCT TOKYO OHKA KOGYO CO LTD (JP) 2026-03-26 US disclosed
US-12583973-B2 Polyimide-based polymer, positive photosensitive resin composition, negative photosensitive resin composition, patterning method, method for forming cured film, interlayer insulating film, surface protective film, and electronic component SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-24 US disclosed
US-20260050218-A1 PHENOLIC HYDROXYL GROUP-CONTAINING BRANCHED ORGANOPOLYSILOXANE, HIGH ENERGY RAY-CURABLE COMPOSITION CONTAINING SAME, AND USE THEREOF DOW TORAY CO LTD (JP) 2026-02-19 US disclosed
US-20260049187-A1 CO-MODIFIED BRANCHED ORGANOPOLYSILOXANE, HIGH ENERGY RAY-CURABLE COMPOSITION CONTAINING SAME, AND USE OF SAME DOW TORAY CO LTD (JP) 2026-02-19 US disclosed
US-12552888-B2 Curable resin composition and display device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2026-02-17 US disclosed
US-6268108-B1 MIXTURE OF COMPOUND FORMING ACID UPON EXPOSURE OF ACTINIC RADIATION, COMPOUND CAPABLE OF CROSSLINKING, DYE AND SOLVENT TOKYO OHKA KOGYO CO., LTD. (JP) 2001-07-31 US disclosed
US-20010004511-A1 Pigment-dispersion photo-sensitive coating solution SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2001-06-21 US disclosed
EP-1103856-A1 Positive resist composition & process for forming resist pattern using same Central Glass Company, Limited (JP) 2001-05-30 EP disclosed
US-6225476-B1 ACRYLIC ESTER COMPOUND HAVING ALKOXYCARBONYL GROUP OR GROUP DERIVED FROM MOLECULE OF LACTONE COMPOUND BY REMOVING HYDROGEN ATOM BONDED TO CARBON ATOM; MONOMER OF FILM-FORMING RESIN TOKYO OHKA KOGYO CO., LTD. (JP) 2001-05-01 US disclosed
US-6190833-B1 (A) A PHENOL RESIN, (B) AN AMINO RESIN, (C) A COMPOUND HAVING TWO OR MORE CROSSLINKING GROUPS IN A MOLECULE, AND (D) A HALOMETHYL-1,3,5-TRIAZINE COMPOUND. JSR CORPORATION (JP) 2001-02-20 US disclosed
US-6183934-B1 FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE KABUSHIKI KAISHA TOSHIBA (JP) 2001-02-06 US disclosed
US-6087063-A Positive-working photoresist composition TOKYO OHKA KOGYO CO., LTD. (JP) 2000-07-11 US disclosed
EP-0915381-A1 Process of forming a pattern on a substrate JSR Corporation (JP) 1999-05-12 EP disclosed
US-5368783-A Novolak resin or polyhydroxystyrene resin, alkoxymethylated amino resin and triazine TOKYO OHKA KOGYO CO., LTD. (JP) 1994-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085194-A1 OPTICAL PRODUCT PFN1, CFL1, C9 GRM4 1933/4885MEN1 4243/4885KMT2A 2846/4885
US-12552888-B2 Curable resin composition and display device RAD51, LPO, FTO GRM4 2227/4885MEN1 4823/4885KMT2A 1001/4885
US-20260050218-A1 PHENOLIC HYDROXYL GROUP-CONTAINING BRANCHED ORGANOPOLYSILOXANE, HIGH ENERGY RAY-CURABLE COMPOSITION CONTAINING SAME, AND USE THEREOF MSR1, HAO2, HAO1 GRM4 2607/4885MEN1 1200/4885KMT2A 1660/4885
US-20260049187-A1 CO-MODIFIED BRANCHED ORGANOPOLYSILOXANE, HIGH ENERGY RAY-CURABLE COMPOSITION CONTAINING SAME, AND USE OF SAME MSR1, HAO2, COL2A1 GRM4 1195/4885MEN1 1335/4885KMT2A 1184/4885
US-20260098128-A1 CURABLE BRANCHED ORGANOPOLYSILOXANE, HIGH ENERGY RAY-CURABLE COMPOSITION CONTAINING SAME, AND USE THEREOF COL2A1, COL1A1, SEM1 GRM4 3001/4885MEN1 2656/4885KMT2A 1699/4885
US-20260117026-A1 DIELECTRIC MATERIALS BASED ON HETEROAROMATIC-EXTENDED BISMALEIMIDES KCNE1, GLRB, PBRM1 GRM4 383/4885MEN1 1824/4885KMT2A 1059/4885
US-12583973-B2 Polyimide-based polymer, positive photosensitive resin composition, negative photosensitive resin composition, patterning method, method for forming cured film, interlayer insulating film, surface protective film, and electronic component PRDM9, ARCN1, PUF60 GRM4 913/4885MEN1 2185/4885KMT2A 537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.