SCHEMBL28396458

SCHEMBL28396458

NC(=O)c1nc(Cl)nc(Cl)n1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
ALDH1A1 P00352 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.40
POLB P06746 1/20 0.39
KDM4E B2RXH2 1/20 0.36
HTT P42858 1/20 0.36
SIRT6 Q8N6T7 1/20 0.33
F2 P00734 1/20 0.31
CFTR P13569 1/20 0.30
PDPK1 O15530 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL697365 0.82 ALDH1A1 (0.57) LMNAALDH1A1ALOX15TSHRPOLB
SCHEMBL1088195 0.78 MAPK1 (0.48) LMNAALDH1A1ALOX15TSHRMAPK1
SCHEMBL7692962 0.74 TSHR (0.47) LMNAALDH1A1ALOX15TSHRMAPK1
SCHEMBL27462527 0.74 POLB (0.41) LMNAALDH1A1TSHRMAPK1POLB
SCHEMBL4161034 0.74 LMNA (0.38) LMNAMAPK1POLBKDM4EHTT
SCHEMBL2854934 0.74 LMNA (0.48) LMNAALDH1A1MAPK1POLBKDM4E
SCHEMBL14434331 0.72 POLB (0.48) LMNAALDH1A1TSHRMAPK1POLB
SCHEMBL10717678 0.72 ALDH1A1 (0.38) LMNAALDH1A1ALOX15TSHR
SCHEMBL9137101 0.70 POLB (0.52) LMNAALDH1A1ALOX15TSHRMAPK1
Acetone SCHEMBL10636901 0.69 ALDH1A1 (0.57) LMNAALDH1A1ALOX15TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111118233-B Organic chloride tanning agent containing salicylic acid structure and preparation method thereof 温州大学 2022-04-01 CN claimed
CN-111118234-B Non-chrome leather tanning method 温州大学 2022-02-15 CN claimed
CN-111118234-A Non-chrome leather tanning method 温州大学 2020-05-08 CN claimed
CN-111118233-A Organic chloride tanning agent containing salicylic acid structure and preparation method thereof 温州大学 2020-05-08 CN claimed
CN-111118233-B Organic chloride tanning agent containing salicylic acid structure and preparation method thereof 温州大学 2022-04-01 CN disclosed
CN-111118234-B Non-chrome leather tanning method 温州大学 2022-02-15 CN disclosed
CN-111118234-B Non-chrome leather tanning method 温州大学 2022-02-15 CN disclosed
CN-111118234-A Non-chrome leather tanning method 温州大学 2020-05-08 CN disclosed
CN-111118233-A Organic chloride tanning agent containing salicylic acid structure and preparation method thereof 温州大学 2020-05-08 CN disclosed
CN-111118234-A Non-chrome leather tanning method 温州大学 2020-05-08 CN disclosed