Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145053 | 0.87 | CASR (0.57) | TSHRALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2840670 | 0.85 | HTR2C (0.40) | MAPK14LTA4HGRM5 | |
| SCHEMBL2839694 | 0.84 | CYP1A2 (0.43) | TSHRALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2837296 | 0.83 | CASR (0.49) | TSHRALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2838847 | 0.83 | CASR (0.55) | TSHRALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4138596 | 0.82 | CASR (0.51) | TSHRALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2838115 | 0.81 | CASR (0.55) | TSHRALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2835830 | 0.78 | CASR (0.66) | TSHRALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13851597 | 0.77 | CASR (0.58) | TSHRALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4138763 | 0.77 | CASR (0.63) | TSHRALDH1A1LMNACASRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039913-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | disclosed |