Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 4/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28399232 | 0.80 | PYCR1 (0.34) | PYCR1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL1417852 | 0.79 | CA1 (0.55) | MIFCA12CA1CA2CA7 | |
| SCHEMBL28394094 | 0.77 | PYCR1 (0.33) | PYCR1MIFHTR3EHTR3BHTR3A | |
| SCHEMBL28397787 | 0.77 | PYCR1 (0.33) | PYCR1 | |
| SCHEMBL17513683 | 0.76 | MIF (0.41) | MIFRAB9AMAPTALDH1A1 | |
| SCHEMBL23465170 | 0.74 | CA1 (0.48) | MIFCA12CA1CA2CA7 | |
| SCHEMBL18245365 | 0.72 | NAAA (0.38) | MIFNOS3HTR3EHTR3BHTR3A | |
| SCHEMBL27972070 | 0.72 | ACHE (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23341680 | 0.69 | CA1 (0.42) | MIFCA12CA1CA2CA7 | |
| SCHEMBL7620598 | 0.69 | CA1 (0.52) | MIFCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116483-B | 2-imidazolyl imidazole compound and preparation method thereof | 浙江师范大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-111116483-A | 2-imidazolyl imidazole compound and preparation method thereof | 浙江师范大学 | 2020-05-08 | — | — | CN | disclosed |