Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28394094 | 0.81 | PYCR1 (0.33) | PYCR1HTR3ESLC22A2SLC22A1SLC22A3 | |
| SCHEMBL28397787 | 0.81 | PYCR1 (0.33) | PYCR1SLC22A2SLC22A1SLC22A3TRPA1 | |
| SCHEMBL28397252 | 0.80 | PYCR1 (0.39) | PYCR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL17513683 | 0.80 | MIF (0.41) | TRPA1L3MBTL1 | |
| SCHEMBL30084661 | 0.79 | HTR3E (0.40) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL18245040 | 0.78 | NOS3 (0.36) | HTR3ESLC22A2SLC22A1SLC22A3HTR3B | |
| SCHEMBL159755 | 0.76 | ACHE (0.47) | HTR3ESLC22A2SLC22A1SLC22A3HTR3B | |
| SCHEMBL18245360 | 0.74 | NOS3 (0.34) | HTR3ESLC22A2SLC22A1SLC22A3HTR3B | |
| SCHEMBL28401806 | 0.74 | TSHR (0.37) | TRPA1TSHRACHETDP1 | |
| SCHEMBL11430813 | 0.74 | HTR3E (0.40) | HTR3ESLC22A2SLC22A1SLC22A3HTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116483-B | 2-imidazolyl imidazole compound and preparation method thereof | 浙江师范大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-111116483-A | 2-imidazolyl imidazole compound and preparation method thereof | 浙江师范大学 | 2020-05-08 | — | — | CN | disclosed |