Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348917 | 0.80 | ALDH1A1 (0.36) | ALDH1A1LMNA | |
| SCHEMBL28348491 | 0.78 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL28368246 | 0.76 | GSK3B (0.41) | ALDH1A1 | |
| SCHEMBL28348392 | 0.72 | HRH4 (0.48) | ALDH1A1LMNA | |
| SCHEMBL14915069 | 0.68 | HPGD (0.41) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28397526 | 0.67 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28394817 | 0.67 | TP53 (0.40) | ALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL28400024 | 0.66 | LMNA (0.43) | ALDH1A1LMNA | |
| SCHEMBL28391828 | 0.66 | KMT2A (0.50) | ALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL28401171 | 0.66 | LMNA (0.45) | ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586484-B | Thienopyran carboxamides and their use | 沈阳药科大学 | 2020-05-15 | — | — | CN | claimed |
| CN-108586484-B | Thienopyran carboxamides and their use | 沈阳药科大学 | 2020-05-15 | — | — | CN | disclosed |