Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | DAO | P14920 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | RXRB | P28702 | 3/20 | 0.33 |
| ▸ | RXRG | P48443 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | RARG | P13631 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348491 | 0.82 | KDM4E (0.31) | ALDH1A1KDM4E | |
| SCHEMBL28368246 | 0.82 | GSK3B (0.41) | ALDH1A1MAPT | |
| SCHEMBL28397646 | 0.80 | ALDH1A1 (0.31) | ALDH1A1LMNA | |
| SCHEMBL28348392 | 0.78 | HRH4 (0.48) | ALDH1A1KDM4EKMT2AHPGDLMNA | |
| SCHEMBL28397526 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL28367955 | 0.73 | MAPT (0.42) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL28400024 | 0.72 | LMNA (0.43) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL28345475 | 0.69 | CA2 (0.51) | ALDH1A1KDM4EDAOMAPTKMT2A | |
| SCHEMBL9984694 | 0.68 | DAO (0.41) | ALDH1A1KDM4EDAOMAPTKMT2A | |
| SCHEMBL28348694 | 0.65 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586484-B | Thienopyran carboxamides and their use | 沈阳药科大学 | 2020-05-15 | — | — | CN | disclosed |
| CN-108822125-B | 1- (thieno [2,3-b ] thiopyranoformyl) -4-aliphatic alkyl piperazine compound and medical application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | disclosed |