Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348917 | 0.82 | ALDH1A1 (0.36) | ALDH1A1MAPT | |
| SCHEMBL28348491 | 0.81 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL28397646 | 0.76 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL28364424 | 0.75 | POLB (0.45) | ALDH1A1MAPTHTT | |
| SCHEMBL28367955 | 0.74 | MAPT (0.42) | ALDH1A1MAPT | |
| SCHEMBL28348392 | 0.74 | HRH4 (0.48) | NPC1ALDH1A1RAB9A | |
| SCHEMBL28364516 | 0.73 | MAPT (0.40) | ALDH1A1MAPTHTTRAB9A | |
| SCHEMBL28884420 | 0.72 | ALDH1A1 (0.39) | ALDH1A1MAPT | |
| SCHEMBL28368248 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTHTT | |
| SCHEMBL6121585 | 0.61 | GSK3B (0.55) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484635-B | 4H-thieno [2,3-b ] thiopyran-4-one compound and application thereof | 沈阳药科大学 | 2020-01-31 | — | — | CN | disclosed |