SCHEMBL2839784

SCHEMBL2839784

CC(=O)Sc1ncncn1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
HSP90AA1 P07900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6172570 0.78 ALDH1A1 (0.41) CA12CA1CA2CA4CA7
SCHEMBL147228 0.67
SCHEMBL15530002 0.67
SCHEMBL17468776 0.64 ALOX15 (0.57)
SCHEMBL27789839 0.64 HSP90AA1 (0.42) HSP90AA1
SCHEMBL9706738 0.64 ALOX15 (0.49)
Acetic Acid SCHEMBL27618049 0.63 HSP90AA1 (0.65) L3MBTL1HSP90AA1
Acetone SCHEMBL28182828 0.63 LMNA (0.50) CA1L3MBTL1
Acetic Acid SCHEMBL7978635 0.62 NQO2 (0.37) HSP90AA1
SCHEMBL9948710 0.62 L3MBTL1 (0.50) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010056914-A1 BACTERIAL HELICASE INHIBITOR COMPOUNDS AND USES THEREOF MICROBIOTIX, INC. (US) 2010-05-20 WO disclosed
WO-1992010484-A1 HERBICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-06-25 WO disclosed