Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 4/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28400108 | 0.91 | KMT2A (0.39) | KMT2AGRM5MAPK14KCNJ6KCNJ3 | |
| SCHEMBL28396599 | 0.87 | PTGS2 (0.44) | KMT2AGRM5MAPK14KCNJ6KCNJ3 | |
| SCHEMBL28398495 | 0.87 | GRM5 (0.38) | KMT2AGRM5KCNJ6KCNJ3KCNJ5 | |
| SCHEMBL28405840 | 0.86 | RPA1 (0.36) | GRM5KCNJ6KCNJ3KCNJ5MGLL | |
| SCHEMBL28399295 | 0.81 | RIPK1 (0.33) | MGLLRIPK1 | |
| SCHEMBL28398225 | 0.80 | SMN1; SMN2 (0.39) | KMT2AMAPK14HTTPOLB | |
| SCHEMBL28395388 | 0.80 | RECQL (0.34) | HTTPTGS2 | |
| SCHEMBL28392426 | 0.80 | MAPT (0.40) | KMT2AGRM5HTTPTGS2POLB | |
| SCHEMBL28397377 | 0.80 | GRM5 (0.36) | GRM5KCNJ6KCNJ3KCNJ5PTGS2 | |
| SCHEMBL28392588 | 0.79 | ALDH1A1 (0.44) | KMT2AMAPK14HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108203450-B | Preparation method and application of amino phosphonate containing arylpyrazole compound | 南京工业大学 | 2020-05-19 | — | — | CN | disclosed |