Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28398492 | 0.90 | BCAT1 (0.38) | GRM5NTRK1BCAT1KDM4EALDH1A1 | |
| SCHEMBL28396599 | 0.88 | PTGS2 (0.44) | GRM5KDM4EMAPTKMT2AGAA | |
| SCHEMBL28398225 | 0.88 | SMN1; SMN2 (0.39) | ALDH1A1MAPTTDP1KMT2AGAA | |
| SCHEMBL28395388 | 0.88 | RECQL (0.34) | ALDH1A1MAPTGAALMNATSHR | |
| SCHEMBL28392426 | 0.88 | MAPT (0.40) | GRM5KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL28400109 | 0.87 | KMT2A (0.39) | GRM5KMT2AKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL28405840 | 0.87 | RPA1 (0.36) | GRM5LMNAKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL28392588 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AGAALMNA | |
| SCHEMBL28397377 | 0.84 | GRM5 (0.36) | GRM5MAPTKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL28399295 | 0.83 | RIPK1 (0.33) | KDM4EALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108203450-B | Preparation method and application of amino phosphonate containing arylpyrazole compound | 南京工业大学 | 2020-05-19 | — | — | CN | disclosed |