SCHEMBL28400263

SCHEMBL28400263

Oc1ccc(-c2nnn[nH]2)cc1.[PbH2]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.43
MAPT P10636 2/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
USP2 O75604 1/20 0.43
TP53 P04637 1/20 0.43
NFKB1 P19838 1/20 0.43
RAB9A P51151 1/20 0.43
NFKB2 Q00653 1/20 0.43
KMT2A Q03164 1/20 0.43
RELA Q04206 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
GAA P10253 1/20 0.41
ALOX12 P18054 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
ESR1 P03372 2/20 0.40
ESR2 Q92731 1/20 0.40
RPS6KA3 P51812 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL595369 0.98 PKM (0.44) PKMMAPTMEN1NPC1USP2
SCHEMBL672712 0.96 ESR1 (0.46) PKMMAPTMEN1NPC1USP2
SCHEMBL2028396 0.87 ADH5 (0.32)
SCHEMBL13411813 0.84 ADH5 (0.36)
SCHEMBL673067 0.82 ESR1 (0.57) MEN1KMT2AESR1ESR2MMP3
SCHEMBL9941579 0.81 ESR1 (0.56) ESR1ESR2
SCHEMBL9155822 0.80 ABL1 (0.47) PKMMAPTMEN1NPC1USP2
SCHEMBL23488248 0.79 KDM4E (0.31) ALDH1A1
SCHEMBL17254301 0.79 SNCA (0.35) MAPTMEN1USP2KMT2AALOX12
SCHEMBL27844873 0.78 NR1H2 (0.42) MEN1NPC1RAB9AKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106800658-B 4- (1H-tetrazole-5-yl) phenol lead coordination polymer and synthesis method and application thereof 哈尔滨工业大学 2020-04-24 CN claimed
CN-106800658-B 4- (1H-tetrazole-5-yl) phenol lead coordination polymer and synthesis method and application thereof 哈尔滨工业大学 2020-04-24 CN disclosed
CN-106800658-B 4- (1H-tetrazole-5-yl) phenol lead coordination polymer and synthesis method and application thereof 哈尔滨工业大学 2020-04-24 CN disclosed
CN-106800658-B 4- (1H-tetrazole-5-yl) phenol lead coordination polymer and synthesis method and application thereof 哈尔滨工业大学 2020-04-24 CN disclosed