SCHEMBL2840115

SCHEMBL2840115

Cc1ccc(N)c(N(C)C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.54
ALOX15 P16050 2/20 0.54
CYP3A4 P08684 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TP53 P04637 1/20 0.54
THRB P10828 1/20 0.54
ALDH1A1 P00352 4/20 0.46
CHEK1 O14757 1/20 0.43
NEK2 P51955 1/20 0.43
LIMK1 P53667 1/20 0.43
DYRK1A Q13627 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
HSD17B10 Q99714 1/20 0.43
GAA P10253 2/20 0.42
KMT2A Q03164 1/20 0.42
CA1 P00915 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
TSHR P16473 2/20 0.41
MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19088749 0.84 TDP1 (0.52) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL2409781 0.81 GAA (0.57) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL20068298 0.80 CYP3A4 (0.48) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL19633546 0.79 TDP1 (0.46) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL1708820 0.78 CHEK1 (0.45) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL5641724 0.77 ALDH1A1 (0.43) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL11524424 0.76 ALDH1A1 (0.48) TDP1ALOX15CYP3A4TP53ALDH1A1
SCHEMBL1341419 0.76 S100B (0.50) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL20073375 0.76 TDP1 (0.43) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL1339989 0.76 TDP1 (0.43) TDP1ALOX15CYP3A4SMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5242830-A Detection of impact with fluorescent indicators by embedding microcapsules and releasing HUTCHINSON (FR) 1993-09-07 US claimed
EP-0410287-A2 Polyphosphazene derivatives containing carbonyl groups and variously alkylated tertiary amino groups CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1991-01-30 EP claimed
EP-3508190-B1 LIGHT CURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2022-02-09 EP disclosed
EP-1454921-B1 RADICAL POLYMERIZATION CATALYSTS AND ADHESIVE KIT FOR DENTAL USE TOKUYAMA CORP (JP) 2021-07-28 EP disclosed
US-10828240-B2 Light curable composition TOKUYAMA DENTAL CORPORATION (JP) 2020-11-10 US disclosed
CN-106146851-B Photocurable composition and cured product containing same 信越化学工业株式会社 2020-10-23 CN disclosed
EP-3093303-B1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT SHINETSU CHEMICAL CO (JP) 2019-08-28 EP disclosed
EP-3508190-A1 PHOTOCURABLE COMPOSITION Tokuyama Dental Corporation (JP) 2019-07-10 EP disclosed
US-20190192386-A1 LIGHT CURABLE COMPOSITION TOKUYAMA DENTAL CORPORATION (JP) 2019-06-27 US disclosed
US-10280122-B2 Treatment of subterranean formations with self-healing resins HALLIBURTON ENERGY SERVICES, INC. (US) 2019-05-07 US disclosed
CN-109640924-A Photocurable composition 株式会社德山齿科 2019-04-16 CN disclosed
US-20050009946-A1 Radical polymerization catalyst and adhesive kit for dental use TOKUYAMA CORPORATION (JP) 2005-01-13 US disclosed
US-6815470-B2 FOR DENTAL RESTORATIVE, DOES NOT CAUSE THE CURED PRODUCT TO BE TINTED OR DISCOLORED TOKUYAMA CORPORATION (JP) 2004-11-09 US disclosed
EP-1454921-A1 RADICAL POLYMERIZATION CATALYSTS AND ADHESIVE KIT FOR DENTAL USE Tokuyama Corporation (JP) 2004-09-08 EP disclosed
US-20040006154-A1 Deantal catalyst for chemical polymerization and use thereof IBARAGI KAZUYA (JP) 2004-01-08 US disclosed
US-6660784-B2 Adhesives; mixture of peroxy compounds and tetraphenylborate as catalyst TOKUYAMA CORPORATION (JP) 2003-12-09 US disclosed
US-20020132951-A1 Dental catalyst for chemical polymerization and use thereof TOKUYAMA CORPORATION 2002-09-19 US disclosed
EP-1190695-A1 Catalyst for chemical polymerization of dental materials TOKUYAMA CORPORATION (JP) 2002-03-27 EP disclosed
US-5338769-A Acrylated polycarbonate, organic polymer fine powder, photoinitiator MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-08-16 US disclosed
EP-0499435-A2 Photo-curable resin composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-08-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040006154-A1 Deantal catalyst for chemical polymerization and use thereof MPO, DBN1, BRD1 TDP1 262/4885ALOX15 385/4885CYP3A4 1883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.