Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | NEK2 | P51955 | 1/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7809579 | 0.88 | ALDH1A1 (0.53) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL19983112 | 0.83 | CASP1 (0.41) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL3677213 | 0.82 | CYP3A4 (0.46) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL11811790 | 0.82 | CYP3A4 (0.46) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL7406313 | 0.80 | GAA (0.59) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL865227 | 0.78 | ALDH1A1 (0.54) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL2840115 | 0.78 | TDP1 (0.54) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL11524424 | 0.78 | ALDH1A1 (0.48) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL3794551 | 0.78 | MAOA (0.50) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL24773629 | 0.76 | CHEK1 (0.42) | CHEK1NEK2LIMK1DYRK1ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8325223-A | — | — | None | — | — | JP | disclosed |
| CN-112409998-A | Photo-thermal conversion eutectic material containing N, N, N, N-tetramethyl-p-phenylenediamine and preparation method thereof | 汕头大学 | 2021-02-26 | — | — | CN | disclosed |
| US-9658234-B2 | Method for analysis of compounds with amino group and analytical reagent therefor | AJINOMOTO CO., INC. (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9598608-B2 | Soluble, processable polyhemiaminals and polyhexahydrotriazines | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-03-21 | — | — | US | disclosed |
| US-9512332-B2 | Soluble, processable polyhemiaminals and polyhexahydrotriazines | INTERNATIONAL BUSUINESS MACHINES CORPORATION (US) | 2016-12-06 | — | — | US | disclosed |
| US-20160139134-A1 | METHOD FOR ANALYSIS OF COMPOUNDS WITH AMINO GROUP AND ANALYTICAL REAGENT THEREFOR | AJINOMOTO CO., INC. (JP) | 2016-05-19 | — | — | US | disclosed |
| US-9274123-B2 | Method for analysis of compounds with amino group and analytical reagent therefor | AJINOMOTO CO., INC. (JP) | 2016-03-01 | — | — | US | disclosed |
| US-9238204-B2 | Gas separation composite membrane and gas separating module, gas separation apparatus and gas separation method using the same | FUJIFILM CORPORATION (JP) | 2016-01-19 | — | — | US | disclosed |
| US-20150376442-A1 | SOLUBLE, PROCESSABLE POLYHEMIAMINALS AND POLYHEXAHYDROTRIAZINES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2015-12-31 | — | — | US | disclosed |
| US-20150376451-A1 | SOLUBLE, PROCESSABLE POLYHEMIAMINALS AND POLYHEXAHYDROTRIAZINES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2015-12-31 | — | — | US | disclosed |
| US-20040259186-A1 | Detection of oxidizing agents in urine | ARMY, UNITED STATES | 2004-12-23 | — | — | US | disclosed |
| EP-1475632-A1 | METHOD OF ANALYZING AMINOFUNCTIONAL COMPOUND AND ANALYTICAL REAGENT | Ajinomoto Co., Inc. (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-20040198830-A1 | Carbamic acid compounds comprising an ether linkage as hdac inhibitors | TOPOTARGET UK LIMITED (GB) | 2004-10-07 | — | — | US | disclosed |
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | disclosed |
| EP-1003737-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS HFGAN72 ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999009024-A1 | PHENYL UREA AND PHENYL THIOUREA DERIVATIVES AS HFGAN72 ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1999-02-25 | — | — | WO | disclosed |
| JP-H08325223-A | UREA DERIVATIVE, ITS PRODUCTION AND HEAT-SENSITIVE TYPE DIAZO RECORDING MATERIAL USING THE SAME | RICOH CO LTD | 1996-12-10 | — | — | JP | disclosed |
| US-5561198-A | DIALKYL ANILINE DERIVATIVES; RADIATION TRANSPARENT; NONTOXIC; ODORLESS; BONDING STRENGTH | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1996-10-01 | — | — | US | disclosed |
| US-5428115-A | N,N-dialkyl aniline derivatives as end groups of polymers or oligomers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-06-27 | — | — | US | disclosed |
| WO-1992018547-A1 | ACTIVATOR FOR CYANOACRYLATE ADHESIVES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1992-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198830-A1 | Carbamic acid compounds comprising an ether linkage as hdac inhibitors | HDAC1, HDAC11, HDAC3 | CHEK1 2135/4885NEK2 1860/4885LIMK1 1929/4885 |
| US-20160139134-A1 | METHOD FOR ANALYSIS OF COMPOUNDS WITH AMINO GROUP AND ANALYTICAL REAGENT THEREFOR | CTH, VIP, SLC7A11 | CHEK1 4339/4885NEK2 4640/4885LIMK1 4845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.