Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22366404 | 0.94 | TDP1 (0.46) | TDP1STK17BSTK17ADRD2MAOA | |
| SCHEMBL13975444 | 0.86 | LMNA (0.47) | TDP1STK17BSTK17ADRD2CCNC | |
| SCHEMBL16245608 | 0.83 | TDP1 (0.44) | TDP1STK17BSTK17ADRD2MAOA | |
| SCHEMBL22012670 | 0.83 | TDP1 (0.47) | TDP1STK17BSTK17ADRD2MAOA | |
| SCHEMBL31627058 | 0.81 | TDP1 (0.44) | TDP1STK17BSTK17ADRD2MAOA | |
| SCHEMBL19027486 | 0.81 | DRD2 (0.45) | TDP1STK17BSTK17ADRD2MAOA | |
| SCHEMBL13165704 | 0.80 | MEN1 (0.45) | TDP1STK17BSTK17ADRD2MAOA | |
| SCHEMBL16245563 | 0.80 | TDP1 (0.47) | TDP1STK17BSTK17ADRD2MAOA | |
| SCHEMBL20140741 | 0.80 | L3MBTL1 (0.52) | TDP1STK17BSTK17ADRD2MAOA | |
| SCHEMBL25014637 | 0.79 | TDP1 (0.49) | TDP1STK17BSTK17ADRD2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111225917-A | Substituted imidazopyridine amides and uses thereof | 拜耳股份公司 | 2020-06-02 | — | — | CN | disclosed |