Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ITK | Q08881 | 4/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6406795 | 0.79 | GSK3B (0.44) | KDM4EHSD17B10AURKAAURKBGSK3B | |
| SCHEMBL28405187 | 0.79 | PARP1 (0.52) | KDM4EHSD17B10AURKAAURKBGSK3B | |
| SCHEMBL17680533 | 0.78 | AURKA (0.48) | KDM4EHSD17B10AURKAAURKBGSK3B | |
| SCHEMBL693581 | 0.76 | GSK3B (0.59) | KDM4EHSD17B10AURKAAURKBGSK3B | |
| SCHEMBL17680257 | 0.73 | COMT (0.49) | KDM4EHSD17B10AURKAAURKBGSK3B | |
| SCHEMBL14077039 | 0.73 | PARP1 (0.49) | KDM4EHSD17B10AURKAAURKBGSK3B | |
| SCHEMBL30693865 | 0.73 | KDM4E (0.68) | KDM4EHSD17B10CASP1CASP7L3MBTL1 | |
| SCHEMBL374022 | 0.71 | RAB9A (0.74) | KDM4EHSD17B10AURKAAURKBGSK3B | |
| SCHEMBL29631691 | 0.71 | RAB9A (0.74) | KDM4EHSD17B10AURKAAURKBGSK3B | |
| SCHEMBL21318393 | 0.71 | PDGFRB (0.52) | KDM4EHSD17B10L3MBTL1AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111225915-B | Imidazopyridine compounds as PAD inhibitors | 朱比兰特埃皮帕德有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-111225915-A | Imidazopyridine compounds as PAD inhibitors | 朱比兰特埃皮帕德有限公司 | 2020-06-02 | — | — | CN | disclosed |