Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28403676 | 0.91 | MMP1 (0.40) | ALDH1A1KMT2AMEN1MMP1MMP9 | |
| SCHEMBL8633653 | 0.84 | MMP1 (0.42) | ALDH1A1KMT2AMMP1MMP9MMP12 | |
| SCHEMBL4223881 | 0.80 | MMP1 (0.41) | ALDH1A1KMT2AMEN1MMP1MMP9 | |
| SCHEMBL15547130 | 0.76 | CYP3A4 (0.49) | ALDH1A1CA2CYP3A4KMT2AMEN1 | |
| SCHEMBL14989478 | 0.75 | MEN1 (0.49) | ALDH1A1KMT2AMEN1MMP1MMP9 | |
| SCHEMBL1537155 | 0.75 | CA2 (0.48) | ALDH1A1CA2CYP3A4LMNAPRSS1 | |
| SCHEMBL5656608 | 0.74 | MMP1 (0.44) | ALDH1A1KMT2AMEN1MMP1MMP9 | |
| SCHEMBL5041398 | 0.74 | MMP1 (0.44) | ALDH1A1KMT2AMEN1MMP1MMP9 | |
| SCHEMBL17138134 | 0.74 | L3MBTL1 (0.46) | ALDH1A1CA2CYP3A4KMT2AMEN1 | |
| SCHEMBL15670665 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KMT2AMMP1MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060292188-A1 | Ophthalmic solution with a flavoring agent | BAUSCH & LOMB INCORPORATED | 2006-12-28 | — | — | US | claimed |
| WO-2006132870-A1 | OPHTHALMIC SOLUTION WITH A FLAVORING AGENT | BAUSCH & LOMB INCORPORATED (US) | 2006-12-14 | — | — | WO | claimed |
| US-9701177-B2 | Ceramic coated automotive heat exchanger components | HENKEL AG & CO. KGAA (DE) | 2017-07-11 | — | — | US | disclosed |
| US-20130137625-A1 | Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof | SOLARBRE, INC. (US) | 2013-05-30 | — | — | US | disclosed |
| US-8246869-B2 | Photo-responsive microencapsulation materials, compositions and methods of use thereof | SOLARBRE, INC. (US) | 2012-08-21 | — | — | US | disclosed |
| EP-2414764-A2 | CERAMIC COATED AUTOMOTIVE HEAT EXCHANGER COMPONENTS | Henkel AG & Co. KGaA (DE) | 2012-02-08 | — | — | EP | disclosed |
| US-20100252241-A1 | CERAMIC COATED AUTOMOTIVE HEAT EXCHANGER COMPONENTS | HENKEL AG & CO. KGAA (DE) | 2010-10-07 | — | — | US | disclosed |
| WO-2010114988-A2 | CERAMIC COATED AUTOMOTIVE HEAT EXCHANGER COMPONENTS | HENKEL AG & CO. KGAA (DE) | 2010-10-07 | — | — | WO | disclosed |
| US-20090202652-A1 | Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof | SOLARBRE, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| EP-1945344-A2 | PHOTO-RESPONSIVE MICROENCAPSULATION MATERIALS, COMPOSITIONS AND METHODS OF USE THEREOF | Solarbre, Inc. (US) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007051198-A2 | PHOTO-RESPONSIVE MICROENCAPSULATION MATERIALS, COMPOSITIONS AND METHODS OF USE THEREOF | SOLARBRE, INC (US) | 2007-05-03 | — | — | WO | disclosed |
| US-20070014992-A1 | Scented multilayer films and method of making | LONGMOORE KENNETH J | 2007-01-18 | — | — | US | disclosed |
| US-20070014993-A1 | Scented multilayer films and method of making | APPLIED EXTRUSION TECHNOLOGIES, INC. | 2007-01-18 | — | — | US | disclosed |
| US-20060292188-A1 | Ophthalmic solution with a flavoring agent | BAUSCH & LOMB INCORPORATED | 2006-12-28 | — | — | US | disclosed |
| US-20060292189-A1 | Ophthalmic solution with a flavoring agent as a dosing indicator and method for indicating dosage of an ophthalmic solution | BAUSCH & LOMB INCORPORATED | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090202652-A1 | Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof | LIPA, LIPE, CRYAA | ALDH1A1 3388/4885CA2 3940/4885CYP3A4 3144/4885 |
| US-20060292188-A1 | Ophthalmic solution with a flavoring agent | TAS2R60, TAS2R10, TAS2R40 | ALDH1A1 1468/4885CA2 1540/4885CYP3A4 4129/4885 |
| US-20060292189-A1 | Ophthalmic solution with a flavoring agent as a dosing indicator and method for indicating dosage of an ophthalmic solution | TAS2R7, TAS2R40, TAS2R42 | ALDH1A1 364/4885CA2 854/4885CYP3A4 2765/4885 |
| US-20130137625-A1 | Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof | LIPA, LIPE, CRYAA | ALDH1A1 3388/4885CA2 3940/4885CYP3A4 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.