SCHEMBL326468

SCHEMBL326468

O=C(Oc1ccccc1I)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.44
FABP3 P05413 1/20 0.44
FABP5 Q01469 1/20 0.44
ELANE P08246 2/20 0.41
CES1 P23141 2/20 0.36
MLYCD O95822 1/20 0.36
PPARG P37231 1/20 0.33
GAA P10253 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
MAPK1 P28482 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30185696 1.00 FABP7 (0.44) FABP7FABP3FABP5ELANECES1
SCHEMBL28404237 0.86 ELANE (0.47) ELANECES1MLYCDGAAHDAC6
SCHEMBL29372709 0.84 ELANE (0.34) FABP7FABP3FABP5ELANEMLYCD
SCHEMBL44659 0.84 ELANE (0.34) FABP7FABP3FABP5ELANEMLYCD
SCHEMBL24901091 0.84 FABP7 (0.41) FABP7FABP3FABP5ELANEMLYCD
SCHEMBL16868476 0.82 ELANE (0.33) FABP7FABP3FABP5ELANEMLYCD
SCHEMBL28370638 0.81 ELANE (0.62) FABP7FABP3FABP5ELANEMAPT
SCHEMBL25468121 0.79 ELANE (0.44) FABP7FABP3FABP5ELANEGAA
SCHEMBL2651599 0.78 FAAH (0.44) ELANECES1PPARGGAAMAPT
SCHEMBL30523259 0.78 ELANE (0.35) ELANECES1MLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108633-A Preparation method of L-glufosinate intermediate (S) -2- (((benzyloxy) carbonyl) amino) but-3-enoic acid methyl ester 浙江工业大学 2024-05-31 CN claimed
CN-118084706-A Synthesis method of 2- (4-hydroxyphenoxy) benzamide compound 河北科技大学 2024-05-28 CN claimed
CN-118026934-A N-azole-4-methylbenzenesulfonamide compound and preparation method and application thereof 安徽理工大学 2024-05-14 CN claimed
CN-117843600-A Fluorescent probe for detecting hypochlorous acid and preparation method and use method thereof 浙江理工大学 2024-04-09 CN claimed
CN-117486968-A Preparation method of snake venom peptide 深圳创元生物医药科技有限公司 2024-02-02 CN claimed
CN-114539302-B P-type doped material based on triarylboron-nitrogen skeleton, and preparation method and application thereof 广东粤港澳大湾区黄埔材料研究院 2024-02-02 CN claimed
CN-117466915-A Chromone-containing benzo [ d ] imidazo [2,1-b ] thiazole compound and preparation method and application thereof 江西科技师范大学 2024-01-30 CN claimed
CN-117304135-A Synthesis method of 4-substituted-5H-1, 2, 3-dithiazole-5-thione and derivative 衡阳师范学院 2023-12-29 CN claimed
CN-117164545-A Reversible fluorescent probe for detecting hypochlorous acid and preparation method and use method thereof 浙江理工大学 2023-12-05 CN claimed
CN-117126178-A Bisphenol thiazide compound and synthesis method thereof 湘潭大学 2023-11-28 CN claimed
CN-113149879-A Preparation method of 4-seleno-naphthyl ester or 4-seleno-naphthyl amide 温州医科大学 2021-07-23 CN claimed
CN-112979545-A Preparation method of 5-selenoquinoline amide or 5-selenoquinoline ester 温州医科大学 2021-06-18 CN claimed
CN-109293692-B Gem-difluoroalkyl borate compounds and preparation method and application thereof 中山大学 2021-05-11 CN claimed
CN-110483460-B Preparation method of 3-seleno-coumarin compound 温州医科大学 2021-04-20 CN claimed
CN-110698322-B Synthesis method of coastal twinborn anthane diterpene Stemarin 浙江大学 2021-01-26 CN claimed
CN-110776442-A Preparation method of memantine hydrochloride intermediate 华中科技大学 2020-02-11 CN claimed
CN-110698322-A Synthesis method of coastal twinborn anthane diterpene Stemarin 浙江大学 2020-01-17 CN claimed
CN-1062731-A Water soluble camptothecin analogs and intermediates preparation thereof are by the compound and the using method thereof of described method preparation SMITHKLINE BEECHAM CORP (US) 1992-07-15 CN claimed
EP-0127235-B1 PARTIALLY RETRO-INVERTED DECAPEPTIDE AS A SPECIFIC RENIN INHIBITOR WITH HIGH RESISTANCE TO ENZYMATIC HYDROLYSIS ENI-Ente Nazionale Idrocarburi (IT) 1988-10-19 EP claimed
EP-0127234-B1 A RETRO-INVERSO ANALOGUE OF THE (5-14) DECAPEPTIDE OF EQUINE ANGIOTENSINOGEN, AS A SPECIFIC RENIN INHIBITOR WITH HIGH RESISTANCE TO ENZYMATIC HYDROLYSIS ENI-Ente Nazionale Idrocarburi (IT) 1987-09-23 EP claimed