Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL175823 | 0.80 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.80 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.80 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.80 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| SCHEMBL2628977 | 0.78 | CA1 (0.56) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.76 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL156613 | 0.76 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL11771938 | 0.76 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL20704876 | 0.76 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL21443891 | 0.76 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925646-A | Fluorescent probe for detecting mercury ions, solid sensing film, and preparation and application thereof | 湖南大学 | 2023-04-07 | — | — | CN | claimed |
| CN-114010783-B | Multifunctional boron-rich nano targeting preparation based on covalent organic framework material, and preparation method and application thereof | 大连理工大学 | 2022-10-18 | — | — | CN | claimed |
| CN-115207565-A | All-iron flow battery composite diaphragm and preparation method thereof | 北京化工大学 | 2022-10-18 | — | — | CN | claimed |
| CN-114573842-A | High-temperature-resistant reworkable benzoxazine thermosetting resin and synthesis method and application thereof | 山东大学 | 2022-06-03 | — | — | CN | claimed |
| CN-114010783-A | Multifunctional boron-rich nano targeting preparation based on covalent organic framework material, and preparation method and application thereof | 大连理工大学 | 2022-02-08 | — | — | CN | claimed |
| CN-109161027-B | Method for synthesizing and regulating covalent organic framework material by low-temperature plasma induction | 四川大学 | 2021-07-13 | — | — | CN | claimed |
| CN-113078322-A | Graphene-silicon negative electrode material with lithium battery cycling stability and preparation method thereof | 成都新柯力化工科技有限公司 | 2021-07-06 | — | — | CN | claimed |
| CN-108659831-B | Method for preparing solid room temperature phosphorescent carbon dots by one-pot method | 郑州大学 | 2021-03-02 | — | — | CN | claimed |
| CN-112162025-A | Method for detecting cellulose fibers based on electrochemical enzyme sensor | 浙江理工大学 | 2021-01-01 | — | — | CN | claimed |
| CN-111822055-A | Preparation method and application of BiOBr/COF composite photocatalyst | 合肥学院 | 2020-10-27 | — | — | CN | claimed |
| CN-111545251-A | Preparation method of photocatalyst based on graphene molecular framework | 浙江迈实科技有限公司 | 2020-08-18 | — | — | CN | claimed |
| CN-111211317-A | Preparation process of negative electrode material for lithium battery | 合肥克米克科技有限公司 | 2020-05-29 | — | — | CN | claimed |
| CN-115925646-A | Fluorescent probe for detecting mercury ions, solid sensing film, and preparation and application thereof | 湖南大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-114479353-B | Topological interlocking liquid crystal epoxy heat-conducting resin and preparation method and application thereof | 中山大学 | 2023-03-31 | — | — | CN | disclosed |
| CN-115745771-A | Preparation method of biphenyl aromatic conjugated polycarboxylic acid | 常州大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-115505103-A | Conjugated microporous polymer, and organic amine catalytic synthesis method and application thereof | 华中科技大学 | 2022-12-23 | — | — | CN | disclosed |
| CN-111545251-A | Preparation method of photocatalyst based on graphene molecular framework | 浙江迈实科技有限公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-111545251-A | Preparation method of photocatalyst based on graphene molecular framework | 浙江迈实科技有限公司 | 2020-08-18 | — | — | CN | disclosed |
| CN-109433158-B | Magnetic nano composite material for multi-mode peptide fragment enrichment and preparation method and application thereof | 四川大学 | 2020-07-14 | — | — | CN | disclosed |
| CN-111211317-A | Preparation process of negative electrode material for lithium battery | 合肥克米克科技有限公司 | 2020-05-29 | — | — | CN | disclosed |