Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 12/20 | 0.60 |
| ▸ | APP | P05067 | 5/20 | 0.60 |
| ▸ | SNCA | P37840 | 5/20 | 0.60 |
| ▸ | METAP1 | P53582 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13104436 | 1.00 | CMA1 (0.63) | CMA1MAPTAPPSNCAMETAP1 | |
| Dimethylamine SCHEMBL5741201 | 0.93 | CMA1 (0.56) | CMA1MAPTAPPSNCAMETAP1 | |
| SCHEMBL8064186 | 0.90 | CMA1 (0.61) | CMA1MAPTAPPSNCAMETAP1 | |
| SCHEMBL17762754 | 0.83 | MAPT (0.63) | CMA1MAPTAPPSNCAMETAP1 | |
| SCHEMBL1454822 | 0.81 | APP (0.69) | MAPTAPPSNCAMETAP1MAPK1 | |
| SCHEMBL12386751 | 0.81 | APP (0.69) | MAPTAPPSNCAMETAP1MAPK1 | |
| Anthraquinone SCHEMBL28334682 | 0.78 | MEN1 (0.63) | MAPTMAPK1POLBRAB9ANPC1 | |
| SCHEMBL31022832 | 0.77 | MAPT (0.57) | MAPTAPPSNCAMETAP1MAPK1 | |
| SCHEMBL16160384 | 0.77 | MAPT (0.74) | CMA1MAPTAPPSNCAMETAP1 | |
| SCHEMBL3762229 | 0.75 | MAPT (1.00) | CMA1MAPTAPPSNCAMETAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233884-B | Method for synthesizing gamma-butyrolactone containing spiro 1, 3-indandione structure by using microchannel reaction device | 南京工业大学 | 2021-01-26 | — | — | CN | disclosed |
| CN-111233884-A | Method for synthesizing gamma-butyrolactone containing spiro 1, 3-indandione structure by using microchannel reaction device | 南京工业大学 | 2020-06-05 | — | — | CN | disclosed |