Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRY1 | Q16526 | 10/20 | 0.56 |
| ▸ | CRY2 | Q49AN0 | 10/20 | 0.56 |
| ▸ | PER2 | O15055 | 9/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448051 | 0.94 | CRY2 (0.62) | CRY1CRY2PER2 | |
| SCHEMBL28398765 | 0.94 | CRY2 (0.62) | CRY1CRY2PER2 | |
| SCHEMBL28410416 | 0.83 | DNM1 (0.62) | CRY1CRY2PER2DNM1 | |
| SCHEMBL28425309 | 0.82 | BACE1 (0.71) | CRY1CRY2PER2DNM1BACE1 | |
| SCHEMBL29623019 | 0.82 | BACE1 (0.71) | CRY1CRY2PER2DNM1BACE1 | |
| SCHEMBL29622976 | 0.82 | BACE1 (0.71) | CRY1CRY2PER2DNM1BACE1 | |
| SCHEMBL29448056 | 0.80 | BACE1 (0.53) | CRY1CRY2PER2DNM1BACE1 | |
| SCHEMBL28429472 | 0.80 | BACE1 (0.53) | CRY1CRY2PER2DNM1BACE1 | |
| SCHEMBL28402100 | 0.80 | DNM1 (0.58) | CRY1CRY2PER2DNM1 | |
| SCHEMBL28406050 | 0.76 | CRY2 (0.64) | CRY1CRY2PER2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217741-B | Fluorine-substituted monocarbazole derivative, preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2022-03-15 | — | — | CN | disclosed |
| CN-111217741-A | Fluorine-substituted monocarbazole derivative, preparation method and application thereof | 广东省中医院（广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院） | 2020-06-02 | — | — | CN | disclosed |