Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.71 |
| ▸ | PER2 | O15055 | 18/20 | 0.60 |
| ▸ | CRY2 | Q49AN0 | 16/20 | 0.60 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.58 |
| ▸ | CRY1 | Q16526 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28425309 | 1.00 | BACE1 (0.71) | BACE1PER2CRY2DNM1CRY1 | |
| SCHEMBL29622976 | 1.00 | BACE1 (0.71) | BACE1PER2CRY2DNM1CRY1 | |
| SCHEMBL29623020 | 0.92 | PER2 (0.65) | PER2CRY2CRY1 | |
| SCHEMBL28429472 | 0.88 | BACE1 (0.53) | BACE1PER2CRY2DNM1CRY1 | |
| SCHEMBL29448056 | 0.88 | BACE1 (0.53) | BACE1PER2CRY2DNM1CRY1 | |
| SCHEMBL14889275 | 0.84 | BACE1 (1.00) | BACE1PER2DNM1 | |
| SCHEMBL28410416 | 0.84 | DNM1 (0.62) | PER2CRY2DNM1CRY1 | |
| SCHEMBL28406118 | 0.83 | DNM1 (0.88) | DNM1 | |
| SCHEMBL411279 | 0.81 | KMT2A (0.78) | BACE1DNM1 | |
| SCHEMBL15911944 | 0.79 | MAPT (0.58) | PER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285793-B | Fluorine-substituted bimolecular carbazole derivative, and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2022-04-22 | — | — | CN | disclosed |