Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.51 |
| ▸ | RHEB | Q15382 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.40 |
| ▸ | RAF1 | P04049 | 5/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3137293 | 0.87 | GUSB (0.40) | JAK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL28402334 | 0.83 | NPY5R (0.45) | JAK2MAPK14KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28397204 | 0.83 | MAPK13 (0.44) | JAK2RHEBMAPK14MAPK13MAPK12 | |
| SCHEMBL14060462 | 0.80 | PDGFRB (0.38) | JAK2 | |
| SCHEMBL28406040 | 0.79 | IDO1 (0.35) | JAK2 | |
| SCHEMBL28398758 | 0.79 | MAPK13 (0.51) | RHEBMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL28399045 | 0.77 | NPY5R (0.54) | RHEBMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL29712839 | 0.77 | METAP2 (0.42) | JAK2ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL28634816 | 0.77 | METAP2 (0.42) | JAK2ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8311417 | 0.77 | GCGR (0.51) | MAPK14MAPK13MAPK12MAPK11RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057043-A | Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method | 深圳市贝加电子材料有限公司 | 2020-04-24 | — | — | CN | claimed |