SCHEMBL2840799

SCHEMBL2840799

O=S(=O)(O)c1cc(-c2ccc(I)c(S(=O)(=O)O)c2)ccc1I

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.34
HSD17B10 Q99714 2/20 0.34
LMNA P02545 2/20 0.34
HIF1A Q16665 1/20 0.34
TET2 Q6N021 1/20 0.34
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 2/20 0.32
APP P05067 2/20 0.32
MAPT P10636 2/20 0.32
THRB P10828 2/20 0.32
SNCA P37840 2/20 0.32
RECQL P46063 2/20 0.32
BLM P54132 2/20 0.32
KMT2A Q03164 2/20 0.32
ALOX12 P18054 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TTR P02766 1/20 0.31
PIK3C3 Q8NEB9 1/20 0.31
GSTO1 P78417 1/20 0.31
TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18066938 0.82 LMNA (0.50) HPGDHSD17B10LMNAHIF1ATET2
SCHEMBL197382 0.82 RAD51 (0.41) HPGDHSD17B10LMNAHIF1ATET2
SCHEMBL360272 0.78 ALDH1A1 (0.39) HPGDHSD17B10LMNAHIF1AMEN1
SCHEMBL32679848 0.78 ALDH1A1 (0.39) HPGDHSD17B10LMNAHIF1AMEN1
SCHEMBL2791495 0.78 TNNI3 (0.36) HPGDHSD17B10LMNAHIF1ATET2
SCHEMBL4565243 0.78 TET2 (0.35) HPGDHSD17B10LMNAHIF1ATET2
SCHEMBL2564720 0.77 ALDH1A1 (0.38) HPGDHSD17B10LMNAHIF1AMEN1
Potassium SCHEMBL2564722 0.77 ALDH1A1 (0.38) HPGDHSD17B10LMNAHIF1AMEN1
SCHEMBL359489 0.75 CDC25B (0.50) MAPTKMT2ATDP1TSHRSMN1; SMN2
SCHEMBL14074763 0.75 RAD1 (0.39) HPGDHSD17B10LMNAHIF1ATET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120251919-A1 POLYARYLENE-BASED COPOLYMER AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
EP-2489690-A1 POLYARYLENE COPOLYMER AND USES THEREOF Sumitomo Chemical Company Limited (JP) 2012-08-22 EP disclosed
US-20100129729-A1 CEOSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE,CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-05-27 US disclosed
EP-2147943-A1 CROSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE, CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL Sumitomo Chemical Company, Limited (JP) 2010-01-27 EP disclosed
US-20090253015-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) 2009-10-08 US disclosed
US-7375176-B2 Liquid crystal poly(phenylene sulfonic acids) CASE WESTERN RESERVE UNIVERSITY 2008-05-20 US disclosed
EP-1857482-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2007-11-21 EP disclosed
US-20050239994-A1 Liquid crystal poly(phenylene sulfonic acids) CASE WESTERN RESERVE UNIVERSITY 2005-10-27 US disclosed