Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 4/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28408256 | 1.00 | MEN1 (0.48) | MEN1KMT2ATRPA1PLAUHTR3E | |
| SCHEMBL28408254 | 1.00 | MEN1 (0.48) | MEN1KMT2ATRPA1PLAUHTR3E | |
| SCHEMBL28410295 | 0.89 | NFE2L2 (0.50) | MEN1KMT2ATRPA1PLAUHTR3E | |
| SCHEMBL28410294 | 0.89 | NFE2L2 (0.50) | MEN1KMT2ATRPA1PLAUHTR3E | |
| SCHEMBL28296333 | 0.89 | NFE2L2 (0.50) | MEN1KMT2ATRPA1PLAUHTR3E | |
| SCHEMBL28410290 | 0.85 | TRPA1 (0.53) | TRPA1PLAUHTR3EHTR3BHTR3A | |
| SCHEMBL28410291 | 0.85 | TRPA1 (0.53) | TRPA1PLAUHTR3EHTR3BHTR3A | |
| SCHEMBL28296320 | 0.85 | TRPA1 (0.53) | TRPA1PLAUHTR3EHTR3BHTR3A | |
| SCHEMBL28411059 | 0.82 | CYP2D6 (0.50) | MEN1KMT2APLAUHTR3EHTR3B | |
| SCHEMBL28411058 | 0.82 | CYP2D6 (0.50) | MEN1KMT2APLAUHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796372-B | Method for preparing polysubstituted alkenyl amidine | 中国科学院化学研究所 | 2020-03-10 | — | — | CN | disclosed |