Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28408390 | 1.00 | LMNA (0.55) | LMNATSHRMAPK1CASP1CASP7 | |
| SCHEMBL28402717 | 0.83 | MAPK1 (0.72) | LMNAMAPK1CASP1CASP7MAPT | |
| SCHEMBL28410934 | 0.80 | CFTR (0.61) | LMNAMAPK1CASP1CASP7MAPT | |
| SCHEMBL28285612 | 0.76 | MAPK1 (0.52) | MAPK1CASP1CASP7MAPTALDH1A1 | |
| SCHEMBL28410236 | 0.75 | ALDH1A1 (0.71) | LMNATSHRMAPK1CASP1CASP7 | |
| SCHEMBL28406737 | 0.73 | MAPT (0.59) | LMNAMAPK1CASP1CASP7MAPT | |
| Methane SCHEMBL28285604 | 0.72 | MAPT (0.58) | LMNAMAPK1CASP1CASP7MAPT | |
| SCHEMBL28285611 | 0.72 | MAPT (0.58) | LMNAMAPK1CASP1CASP7MAPT | |
| SCHEMBL28411339 | 0.71 | MAPT (0.45) | TSHRMAPK1CASP1CASP7MAPT | |
| SCHEMBL18968585 | 0.69 | KDM4E (0.64) | LMNAMAPTALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535086-B | Synthetic method of quinoxaline-2 (1H) -ketone C-3 carboxylate compound | 湖南科技学院 | 2020-05-05 | — | — | CN | disclosed |