Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28406737 | 0.79 | MAPT (0.59) | MAPTALDH1A1MAPK1HPGDHSD17B10 | |
| Methane SCHEMBL28285604 | 0.78 | MAPT (0.58) | MAPTALDH1A1MAPK1HPGDHSD17B10 | |
| SCHEMBL28285611 | 0.78 | MAPT (0.58) | MAPTALDH1A1MAPK1HPGDHSD17B10 | |
| SCHEMBL28402717 | 0.76 | MAPK1 (0.72) | MAPTALDH1A1MAPK1HPGDHSD17B10 | |
| SCHEMBL28285612 | 0.74 | MAPK1 (0.52) | MAPTALDH1A1MAPK1HPGDHSD17B10 | |
| SCHEMBL28410934 | 0.73 | CFTR (0.61) | MAPTALDH1A1MAPK1HPGDSMN1; SMN2 | |
| SCHEMBL28410236 | 0.71 | ALDH1A1 (0.71) | MAPTALDH1A1MAPK1SMN1; SMN2TP53 | |
| SCHEMBL28408388 | 0.71 | LMNA (0.55) | MAPTALDH1A1MAPK1SMN1; SMN2TP53 | |
| SCHEMBL28408390 | 0.71 | LMNA (0.55) | MAPTALDH1A1MAPK1SMN1; SMN2TP53 | |
| SCHEMBL20442126 | 0.70 | KDM4E (0.40) | MAPTALDH1A1MAPK1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535086-B | Synthetic method of quinoxaline-2 (1H) -ketone C-3 carboxylate compound | 湖南科技学院 | 2020-05-05 | — | — | CN | disclosed |