Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RPA1 | P27694 | 1/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28837118 | 0.77 | PTGS2 (0.33) | PDE5AMAPTNPSR1SMN1; SMN2NOTUM | |
| SCHEMBL27896576 | 0.67 | ALDH1A1 (0.33) | PDE5AMAPTPTGS2ALDH1A1LMNA | |
| SCHEMBL10594147 | 0.63 | MEN1 (0.41) | MAPTNPSR1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL9788336 | 0.62 | ALDH1A1 (0.42) | PDE5AMAPTSMN1; SMN2NOTUMPTGS2 | |
| SCHEMBL27369841 | 0.62 | ALDH1A1 (0.43) | PDE5AMAPTSMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL27544479 | 0.60 | NOTUM (0.45) | PDE5AMAPTNOTUMPTGS2ALDH1A1 | |
| SCHEMBL1023193 | 0.59 | CNR1 (0.58) | PDE5AL3MBTL1ALDH1A1LMNAMEN1 | |
| SCHEMBL4832655 | 0.59 | PTGS2 (0.46) | MAPTNPSR1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL4706146 | 0.59 | MEN1 (0.46) | PDE5AMAPTNPSR1GAAL3MBTL1 | |
| SCHEMBL4183860 | 0.58 | PTGS2 (0.60) | SMN1; SMN2L3MBTL1PTGS2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543139-B | Triazolone compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-03-17 | — | — | CN | disclosed |