Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28408483 | 0.77 | PDE5A (0.40) | PTGS2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27712033 | 0.61 | MAPT (0.38) | PTGS2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9252390 | 0.59 | CNR1 (0.53) | PRKCZPDE5ANR3C2 | |
| SCHEMBL28414459 | 0.57 | TP53 (0.46) | PTGS2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27621420 | 0.57 | MGLL (0.32) | HPGD | |
| SCHEMBL27621423 | 0.57 | MGLL (0.35) | HPGD | |
| SCHEMBL28970131 | 0.56 | CACNA1B (0.31) | — | |
| SCHEMBL29333423 | 0.55 | LMNA (0.47) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1569385 | 0.55 | HSD11B1 (0.69) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1569383 | 0.55 | HSD11B1 (0.69) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543139-A | A kind of triadimefon compound and application thereof | 沈阳中化农药化工研发有限公司 | 2017-03-29 | — | — | CN | disclosed |