Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28415259 | 0.89 | MAPT (0.36) | MAPTHTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28421653 | 0.87 | ICMT (0.37) | MAPTICMTKDM4ENPC1RAB9A | |
| SCHEMBL28417336 | 0.86 | MTNR1A (0.41) | MAPTICMTCCKBRNPC1RAB9A | |
| SCHEMBL28409337 | 0.82 | MAPT (0.40) | MAPTHTTICMTKDM4ENPC1 | |
| SCHEMBL28417337 | 0.82 | CES1 (0.34) | CYP1A2CYP2D6CYP2C9CYP2C19HTT | |
| SCHEMBL28413739 | 0.82 | MAPT (0.40) | MAPTNPC1RAB9ASMN1; SMN2SLC6A2 | |
| SCHEMBL28890966 | 0.78 | EBP (0.34) | MAPTSLC6A2L3MBTL1ALDH1A1 | |
| SCHEMBL28409185 | 0.77 | CHRM2 (0.41) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28056660 | 0.76 | ALDH1A1 (0.40) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28056652 | 0.76 | KMT2A (0.40) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303065-B | N- (arylaminoethyl) -3, 1-benzoxazine-2-ketone compound and preparation method and application thereof | 湖南科技大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-111303065-A | N- (arylaminoethyl) -3, 1-benzoxazine-2-ketone compound and preparation method and application thereof | 湖南科技大学 | 2020-06-19 | — | — | CN | disclosed |