Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HEXA | P06865 | 1/20 | 0.39 |
| ▸ | HEXB | P07686 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417336 | 0.90 | MTNR1A (0.41) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28415259 | 0.88 | MAPT (0.36) | MAPTNPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL28417337 | 0.86 | CES1 (0.34) | GAANPC1RAB9ASMN1; SMN2TAS1R3 | |
| SCHEMBL28409185 | 0.83 | CHRM2 (0.41) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28409339 | 0.82 | MAPT (0.43) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28421653 | 0.80 | ICMT (0.37) | MAPTNPC1RAB9AMAOBALDH1A1 | |
| SCHEMBL28409337 | 0.79 | MAPT (0.40) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28890966 | 0.77 | EBP (0.34) | MAPTTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL28891502 | 0.74 | NPC1 (0.32) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28412278 | 0.73 | L3MBTL1 (0.45) | MAPTGAAHEXAHEXBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303065-B | N- (arylaminoethyl) -3, 1-benzoxazine-2-ketone compound and preparation method and application thereof | 湖南科技大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-111303065-A | N- (arylaminoethyl) -3, 1-benzoxazine-2-ketone compound and preparation method and application thereof | 湖南科技大学 | 2020-06-19 | — | — | CN | disclosed |