Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28263597 | 0.84 | CRBN (0.35) | GAACYP1A2CYP2C19LMNAMAPT | |
| SCHEMBL27546498 | 0.81 | TAS1R3 (0.34) | GAASMN1; SMN2ABCB1CASP1TAS1R3 | |
| SCHEMBL9853303 | 0.75 | HPGD (0.38) | GAAHPGDCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL5256946 | 0.72 | GAA (0.38) | GAAHPGDCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL9627791 | 0.71 | MAPT (0.36) | GAAHPGDCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL28811550 | 0.70 | HSD11B1 (0.39) | GAAHPGDCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL8335693 | 0.69 | CYP4F2 (0.53) | GAAHPGDCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL14111349 | 0.68 | MAPT (0.42) | GAAHPGDCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL4714980 | 0.68 | TDP1 (0.42) | GAAHPGDCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL9562462 | 0.67 | GAA (0.42) | GAAHPGDCYP1A2CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269131-B | Process for preparing cyclopropyl ethyl amide by taking tri-n-propylamine as acid acceptor | 江苏飞宇医药科技股份有限公司 | 2021-12-28 | — | — | CN | disclosed |
| CN-111269131-A | Process for preparing cyclopropyl ethyl amide by taking tri-n-propylamine as acid acceptor | 常州飞宇化工有限公司 | 2020-06-12 | — | — | CN | disclosed |