Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989963 | 0.87 | HPGD (0.65) | HPGDKMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL18715343 | 0.86 | HPGD (0.79) | HPGDKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL922567 | 0.82 | HPGD (0.68) | HPGDKMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30175252 | 0.82 | HPGD (0.69) | HPGDKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL8373056 | 0.81 | HPGD (0.72) | HPGDKMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL28239376 | 0.80 | HPGD (0.63) | HPGDKMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL29936750 | 0.80 | HPGD (0.74) | HPGDKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL28404148 | 0.80 | HPGD (0.74) | HPGDKMT2ALMNAALDH1A1KDM4E | |
| SCHEMBL8756555 | 0.79 | MAPK8 (0.78) | HPGDKMT2AALDH1A1KDM4EMAPK8 | |
| SCHEMBL7015936 | 0.79 | MMP13 (0.68) | HPGDLMNAALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111202068-A | N-benzyl benzamide compound and preparation method and application thereof | 西北农林科技大学 | 2020-05-29 | — | — | CN | disclosed |