SCHEMBL922567

SCHEMBL922567

Cc1cccc(CNC(=O)c2cccnc2N)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.68
KDM4E B2RXH2 3/20 0.68
ALDH1A1 P00352 3/20 0.68
HSD17B10 Q99714 1/20 0.68
MMP13 P45452 1/20 0.59
NSD2 O96028 1/20 0.51
KMT2A Q03164 1/20 0.51
THRB P10828 1/20 0.51
ADORA2A P29274 4/20 0.50
ADORA1 P30542 3/20 0.50
POLB P06746 2/20 0.50
ESR1 P03372 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
NR3C1 P04150 1/20 0.48
AURKA O14965 1/20 0.48
RPS6KB1 P23443 1/20 0.48
USP2 O75604 1/20 0.48
PIK3CD O00329 1/20 0.48
ADORA3 P0DMS8 1/20 0.47
ADORA2B P29275 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922644 0.90 HPGD (0.57) HPGDKDM4EALDH1A1HSD17B10MMP13
SCHEMBL920078 0.90 HPGD (0.56) HPGDKDM4EALDH1A1HSD17B10MMP13
SCHEMBL921320 0.88 HPGD (0.54) HPGDKDM4EALDH1A1HSD17B10MMP13
SCHEMBL920245 0.87 HPGD (0.54) HPGDKDM4EALDH1A1HSD17B10NSD2
SCHEMBL921415 0.86 ROCK2 (0.53) HPGDKDM4EALDH1A1HSD17B10NSD2
SCHEMBL27803858 0.86 NSD2 (0.52) HPGDKDM4EALDH1A1HSD17B10NSD2
SCHEMBL920122 0.85 HPGD (0.68) HPGDKDM4EALDH1A1HSD17B10NSD2
SCHEMBL922756 0.85 HPGD (0.52) HPGDKDM4EALDH1A1HSD17B10NSD2
SCHEMBL922542 0.85 ROCK1 (0.57) HPGDKDM4EALDH1A1HSD17B10NSD2
SCHEMBL920896 0.84 POLB (0.58) HPGDKDM4EALDH1A1HSD17B10MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885KDM4E 3657/4885ALDH1A1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.