Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328917 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2MTNR1AMTNR1BHTR2AHTR6 | |
| SCHEMBL6775637 | 0.88 | MTNR1A (0.59) | SMN1; SMN2MTNR1AMTNR1BHTR2AHTR6 | |
| SCHEMBL24328893 | 0.87 | MTNR1A (0.57) | SMN1; SMN2MTNR1AMTNR1BHTR2AHTR6 | |
| SCHEMBL1461062 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AHTR6DRD2 | |
| SCHEMBL1461064 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AHTR6DRD2 | |
| SCHEMBL29809866 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AHTR6DRD2 | |
| SCHEMBL2013303 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AHTR6DRD2 | |
| SCHEMBL18029216 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AHTR6DRD2 | |
| SCHEMBL24328360 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2HTR2AKDM4EMAPTAPAF1 | |
| SCHEMBL28409195 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2HTR2AKDM4EMAPTAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303001-B | Synthesis method of indole mono-substituted 2-hydroxy-3- (1H-indol-3-yl) propionic acid compound | 苏州爱玛特生物科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-111303001-A | Synthesis method of indole mono-substituted 2-hydroxy-3- (1H-indol-3-yl) propionic acid compound | 苏州爱玛特生物科技有限公司 | 2020-06-19 | — | — | CN | disclosed |