Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | DRD3 | P35462 | 5/20 | 0.46 |
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328917 | 0.87 | SMN1; SMN2 (0.60) | MTNR1AMTNR1BHTR2AHTR6DRD2 | |
| SCHEMBL28409765 | 0.87 | SMN1; SMN2 (0.60) | MTNR1AMTNR1BHTR2AHTR6DRD2 | |
| SCHEMBL1461062 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AHTR6DRD2 | |
| SCHEMBL1461064 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AHTR6DRD2 | |
| SCHEMBL2013303 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AHTR6DRD2 | |
| SCHEMBL29809866 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AHTR6DRD2 | |
| SCHEMBL18029216 | 0.86 | KMT2A (0.61) | MTNR1AMTNR1BHTR2AHTR6DRD2 | |
| SCHEMBL24328896 | 0.85 | GPR84 (0.55) | MTNR1AMTNR1BHTR2AKDM4EMAPT | |
| SCHEMBL24328899 | 0.84 | FFAR1 (0.54) | HTR2AKDM4EMAPTAPAF1POLB | |
| SCHEMBL24328258 | 0.84 | GPR84 (0.54) | MTNR1AMTNR1BHTR2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | disclosed |
| WO-2022078416-A1 | NOVEL GLUTAMINE ANALOGS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399297-A1 | Novel Glutamine Analogs | GLUL, GATD3, GLS | MTNR1A 2266/4885MTNR1B 1790/4885HTR2A 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.